CAMILA FRANCO DE CARVALHO

AUTHOR: CAMILA FRANCO DE CARVALHO

TITLE:HEMODYNAMIC EVALUATIONS OF THE UTERINE ARTERY IN BITES WITH PIOMETRA

ADVISOR: ANDRÉIA VITOR COUTO DO AMARAL

DEFENSE DATE: 02/11/2020

ABSTRACT

The objective of this study was to evaluate hemodynamic changes of the uterine artery (systolic peak velocity - VPS; final diastolic velocity - VED; and resistivity index - IR) in open or closed pyometra and correlated with values uterine diameter (DU) and endometrial thickness (EE). Thirty-five female dogs were distributed in three groups: control - CG (n = 12); open pyometra - GPA (n = 11); closed pyometra - GPF (n = 12). Abdominal ultrasonography in B-Mode and pulsed Doppler uterine artery were performed. It was observed DU difference in three groups (CG: 0.65 ± 0.26 cm; GPA: 2.44 ± 0.27 cm; GPF: 3.40 ± 0.28 cm), but the EE was similar between GPA and GPF (GC: 0.1 ± 0.05 cm; GPA: 0.41 ± 0.05 cm; GPF: 0.27 ± 0.05 cm). Regarding hemodynamic indices, high and similar VPS indices were observed in three groups (CG: 32.6 ± 2.38 cm/s; GPA: 24.8 ± 2.48 cm/s; GPF: 29.4 ± 2.59 cm/s); lower VED values CG and no difference in GPA and GPF (CG: 4.38 ± 0.69 cm/s; GPA: 08.48 ± 0.72 cm/s; GPF: 10.49 ± 0.75 cm/s) and lower and similar rates of RI in groups with piometra (GC: 0.85 ± 0.01; GPA: 0.64 ± 0.01; GPF: 0.63 ± 0.01). The observed spectral morphology in GPA and GPF was due to the high speed and low resistivity vascular pattern, different from the CG, with high speed and high resistivity. The correlation analysis showed the hemodynamic indices suffered influence of DU and EE, observed positive correlation between DU and VED (r = 0.62; p <0.01); and negative between DU and IR (r = -0.68; p <0.01) and EE and IR (r = -0.62; p <0.01). It concludes that the hemodynamic alterations of the uterine art are similar in bitches with open or closed piometra, although the uterine diameter and endometrial thickness cause its perfusion reflexes.