ANGELICA FRANCO DE OLIVEIRA

AUTHOR:  ANGELICA FRANCO DE OLIVEIRA
TITLE: CTBL-M ESBL PRODUCING ENTEROBACTERIA PRESENT IN VETERINARY HOSPITAL ENVIRONMENT

ADVISOR:  Prof. Dr. ARIEL EURIDES STELLA
DEFENSE DATE: 04/30/2019

ABSTRACT

Due to the high selective pressure due to the misuse of antibiotics, it has accelerated the natural resistance process of the bacteria, leading to the appearance of more and more constant multiresistant strains. The high number of multiresistant bacteria that have been isolated is a public health problem because they can lead to loss of protection for diseases that are now treatable. Enterobacteria are usually commensal bacteria but can cause infections, and the most important resistance characteristic between them and the production of β-lactamases. In order to better characterize the circulating and potentially infectious microorganisms in veterinary hospitals, this study aimed to identify ESBL-producing enterobacteria of CTX-M type present in a veterinary hospital. Collection of swabs was carried out by objects that come in contact with the patients and with the professionals. A total of 10 samples were obtained, 306 samples of which 118 enterobacteria were identified as follows: Escherichia coli 56, Enterobacter spp 25, Klebsiella spp 19, Proteus mirabilis 13, Serratia spp 03, Citrobacter spp 2. Among the enterobacteria identified 17 produced β-lactamase and 15 of these are CTX-M type. It is great importance to know the bacterial population circulating in the veterinary hospital environment, and its antimicrobial resistance, so that professionals can take appropriate measures to minimize the risks of infection.